Genomic Microevolution of Vibrio cholerae O1, Lake Tanganyika Basin, Africa

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Abstract

Africa’s Lake Tanganyika basin is a cholera hotspot. During 2001–2020, Vibrio cholerae O1 isolates obtained from the Democratic Republic of the Congo side of the lake belonged to 2 of the 5 clades of the AFR10 sublineage. One clade became predominant after acquiring a parC mutation that decreased susceptibility to ciprofloxacin.

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Hounmanou, Y. M. G., Njamkepo, E., Rauzier, J., Gallandat, K., Jeandron, A., Kamwiziku, G., … Quilici, M. L. (2023). Genomic Microevolution of Vibrio cholerae O1, Lake Tanganyika Basin, Africa. Emerging Infectious Diseases, 29(1), 149–153. https://doi.org/10.3201/eid2901.220641

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