Abstract
This study reports two novel 5-fluorouracil-substituted ampelopsin derivatives. The structures of two new derivatives were characterized by elemental analysis, 1H-NMR, 13C-NMR, IR and MS. Their anticancer activities in vitro against two cancer cell lines, K562 and K562/ADR, were investigated using the MTT assay, and the results showed that the two new compounds were more effective than reference drugs such as ampelopsin and verapamil. Copyright © 2010 by the authors.
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Zhou, W. M., He, R. R., Ye, J. T., Zhang, N., & Liu, D. Y. (2010). Synthesis and biological evaluation of new 5-fluorouracil-substituted ampelopsin derivatives. Molecules, 15(4), 2114–2123. https://doi.org/10.3390/molecules15042114
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