Genomic characterization of new variant of hydrogen sulfide (H2s)-producing escherichia coli with multidrug resistance properties carrying the mcr-1 gene in China

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Abstract

Colistin is considered to be a ‘last-resort’ antimicrobial for the treatment of multidrug-resistant Gram-negative bacterial infections. Identification of Enterobacteriaceae, carrying the transferable colistin resistance gene mcr-1, has recently provoked a global health concern. This report presents the first detection of a hydrogen sulfide (H2S)-producing Escherichia coli variant isolated from a human in China, with multidrug resistance (MDR) properties, including colistin resistance by the mcr-1 gene, which could have great implications for the treatment of human infections.

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Biswas, S., Elbediwi, M., Gu, G., & Yue, M. (2020). Genomic characterization of new variant of hydrogen sulfide (H2s)-producing escherichia coli with multidrug resistance properties carrying the mcr-1 gene in China. Antibiotics, 9(2). https://doi.org/10.3390/antibiotics9020080

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