High viral loads of human papillomavirus predict risk of invasive cervical carcinoma

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Abstract

High loads of human papillomavirus (HPV) 16 and HPV 18/45 increase the risk of developing invasive cervical carcinoma, revealing higher risk in percentiles of highest viral loads for HPV 16 (odds ratio (OR) 58.7, 95% confidence interval (CI) 21.9-151.4) compared to HPV 18/45 (OR 3.3, 95% CI 1.5-7.2). Thus, HPV load is a type-dependent risk marker for invasive carcinoma. © 2005 Cancer Research UK.

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Moberg, M., Gustavsson, I., Wilander, E., & Gyllensten, U. (2005). High viral loads of human papillomavirus predict risk of invasive cervical carcinoma. British Journal of Cancer, 92(5), 891–894. https://doi.org/10.1038/sj.bjc.6602436

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