Mutual adhesion of animal cells is intimately linked to Wnt signaling through a shared component: β-catenin, or Armadillo in Drosophila. Recent work indicates how β-catenin shifts from cell adhesion to Wnt signaling, a switch associated with epithelial-mesenchymal transitions and cancer.
Bienz, M. (2005, January 26). β-catenin: A pivot between cell adhesion and Wnt signalling. Current Biology. https://doi.org/10.1016/j.cub.2004.12.058