Synthesis and antiviral activity of novel [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles, [1,2,4]triazolo[3,4-b][1,3,4] thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4] thiadiazepines

Abstract

Starting from the 4-amino-3-(1,3-diphenyl-1H-pyrazol-4-yl)-4,5-dihydro-[1, 2,4] triazole-5(1H)-thione 2, a series of new [1,3,4]thiadiazoles 3, 4, 7 and [1,3,4] thiadiazines 8, 10, 11, 12, 14 were prepared. Also, [1,3,4] thiadiazepines 16-18 could be synthesized. Some of the newly prepared compounds were evaluated for their antiviral potential. © ARKAT.