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The fungus Neurospora crassa displays telomeric silencing mediated by multiple sirtuins and by methylation of histone H3 lysine 9

  • Smith K
  • Kothe G
  • Matsen C
  • et al.
Epigenetics & Chromatin (2008) 1(1)
DOI: 10.1186/1756-8935-1-5
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Abstract

Silencing of genes inserted near telomeres provides a model to investigate the function of heterochromatin. We initiated a study of telomeric silencing in Neurospora crassa, a fungus that sports DNA methylation, unlike most other organisms in which telomeric silencing has been characterized.

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Smith, K. M., Kothe, G. O., Matsen, C. B., Khlafallah, T. K., Adhvaryu, K. K., Hemphill, M., … Selker, E. U. (2008). The fungus Neurospora crassa displays telomeric silencing mediated by multiple sirtuins and by methylation of histone H3 lysine 9. Epigenetics & Chromatin, 1(1). https://doi.org/10.1186/1756-8935-1-5

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