Hypertriglyceridemia-induced pancreatitis in pregnancy: Case review on the role of therapeutic plasma exchange

N/ACitations
Citations of this article
22Readers
Mendeley users who have this article in their library.

Abstract

Gestational hypertriglyceridemia-induced pancreatitis is associated with significant maternal and fetal morbidity and mortality. We report a case of gestational hypertriglyceridemia-induced pancreatitis in a primigravida at 31-weeks gestation, complicated by impending preterm labor and metabolic acidosis requiring hemodialysis. This was successfully managed with therapeutic plasma exchange (TPE), followed by i.v. insulin, low-fat diet, and omega-3. Triglyceride levels stabilized after TPE and the patient underwent an uncomplicated term delivery. In pregnancy, elevated estrogen and insulin resistance exacerbate hypertriglyceridemia. Management is challenging as risks and benefits of treatment options need to be weighed against fetal wellbeing. We discuss management options including a review of previous case reports detailing TPE use, dietary optimization, and delivery timing. This case emphasizes the importance of multidisciplinary care to optimize maternal and fetal outcomes.

Cite

CITATION STYLE

APA

Tan, S. Y. T., Teh, S. P., Kaushik, M., Yong, T. T., Durai, S., Tien, C. J. C., & Gardner, D. S. L. (2021). Hypertriglyceridemia-induced pancreatitis in pregnancy: Case review on the role of therapeutic plasma exchange. Endocrinology, Diabetes and Metabolism Case Reports, 2021(1). https://doi.org/10.1530/EDM-21-0017

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free