Disseminated fusariosis in a patient with acute myeloid leukemia

Abstract

A female patient with myeloid leukemia developed disseminated fusariosis during the period of myelotoxic agranulocytosis after a course of chemotherapy. The disease manifested by high fever, sinusitis, multiple infiltrations of the skin similar to ecthyma gangrenosum. Mycologic analysis of skin biopsy specimen detected mycelial fungi Fusarium spp. Voriconasole therapy during 3 months led to regression of the infectious process.