Cerebellar Developmental Disorders and Cerebellar Nuclei

Abstract

While significant progress has been made in the last 10 years in understanding the development of cerebellar nuclei, they remain a relatively less well-studied cell group in the brain. In this chapter, we review the anatomical organisation of the cerebellar nuclei and their connections to highlight outstanding developmental questions. We then describe recent progress in dissecting the lineages of cerebellar neurons that may point to new understanding of their involvement in congenital clinical disorders.