Background: Vitamin K, a fat soluble vitamin, is a necessary cofactor for the activation of coagulation factors II, VII, IX, X, and protein C and S. In neonatal period, vitamin K deficiency may lead to Vitamin K Deficiency Bleeding (VKDB). Case presentation: We present the case of a 2 months and 20 days Caucasian male, presented for bleeding from the injections sites of vaccines. At birth oral vitamin K prophylaxis was administered. Neonatal period was normal. He was exclusively breastfed and received a daily oral supplementation with 25 μg of vitamin K. A late onset vitamin K deficiency bleeding was suspected. Intravenous Vitamin K was administered with complete recovery. Conclusions: Nevertheless the oral prophylaxis, our case developed a VKDB: it is necessary to revise the current guidelines in order to standardize timing and dosage in different clinical conditions.
CITATION STYLE
Marchili, M. R., Santoro, E., Marchesi, A., Bianchi, S., Rotondi Aufiero, L., & Villani, A. (2018). Vitamin K deficiency: A case report and review of current guidelines. Italian Journal of Pediatrics, 44(1). https://doi.org/10.1186/s13052-018-0474-0
Mendeley helps you to discover research relevant for your work.