Descriptive, Prospective Observational Study- Studying Possible Prediction Factors for Disease Severity and Progression among a Sample of COVD 19 Patients in Iraq

Abstract

Coronavirus has affected many people around the world and caused an increase in the number of hospitalized patients and deaths. The prediction factors may assist the clinician in identifying patients who are at high risk of complications and require further medical attention. We aimed to study the possible relationship between C reactive protein level and the severity of symptoms and its effect on the prognosis of the disease. And determine patients who require closer respiratory monitoring and more aggressive supportive therapies to avoid poor prognosis. The data was gathered using medical record data, the patient's medical history, and the onset of symptoms, as well as a blood sample to test the C-reactive protein level. The patients were divided into three groups based on the severity of the disease. A descriptive, prospective observational study of 246 patients over the age of 18 years discovered that c-reactive protein levels were significantly higher in more severe cases than in mild cases, and that older patients with high levels of AST, TSB, Urea, Creatinine, and CRP were associated with the need for a high flow of oxygen, an intensive care unit, a longer length of hospitalization, and have a high mortality rate. The study concluded several predictor factors for the disease (COVID-19) severity, duration of hospitalization, ICU admission and need for oxygen therapy.