Room-temperature Swern oxidations by using a microscale flow system

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Abstract

(Equation Presented) Residence time controlled reaction: The Swern oxidation of alcohols has been accomplished by using a microscale flow system, consisting of micromixers and microscale tube reactors (see schematic representation ; DMSO = dimethylsulfoxide, TFAA = trifluoroacetic anhydride), at higher temperatures (-20 to 20°C) than those for conventional macroscale batch systems (-50°C or below). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

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Kawaguchi, T., Miyata, H., Ataka, K., Mae, K., & Yoshida, J. I. (2005). Room-temperature Swern oxidations by using a microscale flow system. Angewandte Chemie - International Edition, 44(16), 2413–2416. https://doi.org/10.1002/anie.200462466

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