Complexes with biologically active ligands. Part 6 Ni(II) coordination compounds of hydrazine and heterocyclic sulfonamides as inhibitors of the zinc enzyme carbonic anhydrase

Joaquin Borràs; Javier Casanova; Teodora Cristea; Adriana Gheorghe; Andrea Scozzafava; Claudiu T. Supuran; Violeta Tudor

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Complexes with biologically active ligands. Part 6 Ni(II) coordination compounds of hydrazine and heterocyclic sulfonamides as inhibitors of the zinc enzyme carbonic anhydrase

Metal-Based Drugs (1996) 3(3) 143-148

DOI: 10.1155/MBD.1996.143

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Abstract

Ternary Ni(II) complexes of hydrazine and eight heterocyclic sulfonamides possessing carbonic anhydrase (CA) inhibitory properties, were prepared and characterized by elemental analysis, spectroscopic, magnetic, thermogravimetric, and conductimetric measurements. The complexes behave as strong inhibitors for two isozymes (I and II) of carbonic anhydrase.

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Borràs, J., Casanova, J., Cristea, T., Gheorghe, A., Scozzafava, A., Supuran, C. T., & Tudor, V. (1996). Complexes with biologically active ligands. Part 6 Ni(II) coordination compounds of hydrazine and heterocyclic sulfonamides as inhibitors of the zinc enzyme carbonic anhydrase. Metal-Based Drugs, 3(3), 143–148. https://doi.org/10.1155/MBD.1996.143

Complexes with biologically active ligands. Part 6 Ni(II) coordination compounds of hydrazine and heterocyclic sulfonamides as inhibitors of the zinc enzyme carbonic anhydrase

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