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Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine

Antimicrobial Agents and Chemotherapy (2007) 51(10) 3768-3770
DOI: 10.1128/AAC.00239-07
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Abstract

Trioxaquines, potential antimalarial agents, and heme-artemisinin adducts, resulting from the alkylation of heme by artemisinin, were evaluated as inhibitors of β-hematin formation in 10 M acetate medium at pH 5. Copyright © 2007, American Society for Microbiology. All Rights Reserved.

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Loup, C., Lelièvre, J., Benoit-Vical, F., & Meunier, B. (2007). Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine. Antimicrobial Agents and Chemotherapy, 51(10), 3768–3770. https://doi.org/10.1128/AAC.00239-07

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