CT Colonography versus Colonoscopy for the Detection of Advanced Neoplasia

Abstract

Advanced neoplasia of the large intestine consists of both adenocarcinomas and a subgroup of benign neoplasms referred to as advanced adenomas. The advanced adenoma represents the optimal target lesion for strategies to prevent colorectal cancer. This benign lesion is considered to be associated with a relatively high risk of progression to cancer.1 The advanced adenoma is specifically defined as an adenoma that meets one or more of the following criteria: a size of at least 10 mm, the presence of a substantial villous component, and the presence of high-grade dysplasia.1,2 Removal of detected advanced adenomas effectively disrupts the potential . . .