Abstract
Structural characterization of the colistin (CL) components were carried out using Frit-fast atom bombardment liquid chromatography/mass spectrometry (Frit-FAB LC/MS), tandem mass spectrometry (MS/MS) and the amino acid analysis proposed by MARFEY, and the total structures of 4 minor components including the absolute configuration of the constituent amino acids were proposed. The structures of the minor components were the same as those of the main component colistin A or B except that L-leucine is replaced by L-valine or L-isoleucine.
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CITATION STYLE
Ikai, Y., Oka, H., Hayakawa, J., Kawamura, N., Mayumi, T., Suzuki, M., & Harada, K. I. (1998). Total structures of colistin minor components. Journal of Antibiotics, 51(5), 492–498. https://doi.org/10.7164/antibiotics.51.492
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