Neuroblastoma

Abstract

Neuroblastoma is a common solid tumor of infancy and childhood. It is uniquely characterized by a distinct natural history and prognosis in infants compared with older children. Whereas older children often experience rapidly progressive disease with a poor prognosis, many infants have indolent tumors that may exhibit only minimal progression over time or may even regress entirely. While the prognosis for infants with neuroblastoma is typically optimistic, patients still require multimodal therapy, ideally provided by institutions with expertise in the treatment of pediatric cancers.