Neuroprotection of retinal ganglion cells

Abstract

Therapeutic efforts for treatment of glaucoma have focused on reduction of intraocular pressure as the main objective. In clinical practice, intraocular pressure (IOP) control has been expected to slow or arrest the glaucoma progression. However, clinicians have been confronted with significant glaucoma progression even when achieving control of intraocular pressure. In the Collaborative Normal-Tension Glaucoma Study, following medical or surgical treatment to achieve at least 30% reduction of intraocular pressure, 12% of patients experienced continued visual field loss secondary to optic nerve damage. © 2010 Springer-Verlag New York.