Raman spectroscopy as a modern diagnostic technology for study and indication of infectious agents (Review)

Abstract

The study and detection of causative agents of infectious diseases are an important and urgent task, the progress of which can be achieved only if different approaches are used. Current diagnostic technologies based on different biophysical detection principles allow the research of complex biological substrates with a high degree of analytical reliability. Raman spectroscopy based on the discovery of molecular structure has long established itself as a reliable analytical tool in various fields of science and technology. The purpose of this report is to review current achievements in microbiology using the Raman spectroscopy, demonstration its limitations, as well as the most important world trends in the application of this diagnostic technology for the study and indication of pathogens of bacterial and viral infections.