The past few years have seen new research methods confirm-ing more confidently that glia have a key information processing role in the brain, specifically in relation to learning capability. However, many details Tof glia's role remain unknown, including a gap between cellular and behavioural level findings. Based on Ca 2+ wave mechanics in astro-cytes, we derive a theoretical capability of astrocytes to encode cognitive representations as probability distributions over synapses. The process is analogous to MCMC Bayesian inference that samples a neural network configuration from a prior in the astrocyte and then uses its performance to update to a posterior distribution. The proposed model explains recent behavioural results where obstructing astrocytes leads to deficiencies in learning new knowledge without affecting ability to recall existing knowl-edge. The model is also a novel Bayesian brain theory which uniquely addresses the cellular and synaptic levels.
CITATION STYLE
B, M. D., & An, A. (2016). Computational Role of Astrocytes in Bayesian, 2, 24–33.
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