The modENCODE data coordination center: Lessons in harvesting comprehensive experimental details

25Citations
Citations of this article
53Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

The model organism Encyclopedia of DNA Elements (modENCODE) project is a National Human Genome Research Institute (NHGRI) initiative designed to characterize the genomes of Drosophila melanogaster and Caenorhabditis elegans. A Data Coordination Center (DCC) was created to collect, store and catalog modENCODE data. An effective DCC must gather, organize and provide all primary, interpreted and analyzed data, and ensure the community is supplied with the knowledge of the experimental conditions, protocols and verification checks used to generate each primary data set. We present here the design principles of the modENCODE DCC, and describe the ramifications of collecting thorough and deep metadata for describing experiments, including the use of a wiki for capturing protocol and reagent information, and the BIR-TAB specification for linking biological samples to experimental results. modENCODE data can be found at http:// www.modencode.org. © The Author(s) 2011.

Cite

CITATION STYLE

APA

Washington, N. L., Stinson, E. O., Perry, M. D., Ruzanov, P., Contrino, S., Smith, R., … Lewis, S. E. (2011). The modENCODE data coordination center: Lessons in harvesting comprehensive experimental details. Database, 2011. https://doi.org/10.1093/database/bar023

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free