Glycosylated dihydrochalcones as potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitors

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Abstract

A series of glucose conjugates was synthesized and tested for inhibition of SGLT1 and SGLT2. © 2004 Elsevier Ltd. All rights reserved.

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Dudash, J., Zhang, X., Zeck, R. E., Johnson, S. G., Cox, G. G., Conway, B. R., … Demarest, K. T. (2004). Glycosylated dihydrochalcones as potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitors. Bioorganic and Medicinal Chemistry Letters, 14(20), 5121–5125. https://doi.org/10.1016/j.bmcl.2004.07.082

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