Multimodality Imaging of Danon Disease in a Patient with a Novel LAMP2 Mutation

Abstract

• Danon disease is a rare X-linked genetic disorder of the LAMP2 gene. • Danon cardiomyopathy has a high incidence of preexcitation and severe LVH. • LAMP2 mutation–associated cardiomyopathy can mimic sarcomeric HCM. • Multimodality imaging is key to a successful diagnosis of Danon disease. [Figure: see text] eng