Effect of high intensity interval training on diabetic obese women with polyneuropathy: a randomized controlled clinical trial

Abstract

Purpose: To investigate the effect of high intensity interval training on diabetic obese women with polyneuropathy. Methods: In rehabilitation clinics. A double blinded controlled randomized study including 40 type II diabetic women with polyneuropathy having class II central obesity, mean age 48.23±2.4 years. Patients were randomized equally into Group (A); (study), received high intensity interval training on cycle ergometer and group (B); (control) received moderate intensity aerobic training for (3 times/week) for 15 weeks. Assessment performed before and after treatment using Leeds Assessment of Neuropathic symptoms and signs Scale for pain assessment. Other measures, lower extremity functional scale, body weight, body mass index, waist circumference, and oral glucose tolerance test. Results: There were statistically significant improvement in favor of Group (A) compared to Group (B) in Leeds Assessment of Neuropathic symptoms and signs Scale results with a mean difference (-3.6±0.7 points), (P≤0.0001); waist circumference mean difference (-1.13cm), (P≤0.017). Oral glucose tolerance test had (P≤0.0001): FBG (-6.5±2.9) (P≤0.03), 60 min, 90 min and 120 min mean difference was (-42.75±6.2 mg/dl), (-32.5±4.5 mg/dl) and (-20.15±2.2 mg/dl) respectively. However, lower extremity functional scale, body weight and body mass index did not show a significant difference between both groups. Conclusion: high intensity interval training was effective in reducing pain outcome and glucose tolerance in diabetic obese women with polyneuropathy compared to moderate aerobic intensity training.