A stochastic model is proposed to describe time-dependent lethal effects of toxic compounds. It is based on simple mechanistic assumptions and provides a measure for the toxicity of a chemical compound, the so-called killing rate. The killing rate seems a promising alternative for the LC50. The model also provides the no-effect level and the LC50, both as a function of exposure time. The model is applied to real data and to simulated data. © 1994 Chapman & Hall.
CITATION STYLE
Bedaux, J. J. M., & Kooijman, S. A. L. M. (1994). Statistical analysis of bioassays, based on hazard modelling. Environmental and Ecological Statistics, 1(4), 303–314. https://doi.org/10.1007/BF00469427
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