Enfermedad de Dupuytren en una población del noroeste de España: Hallazgos clínicos en 184 pacientes

Abstract

The goal of this paper is to study the classical factors related to Dupuytren Disease in the patients of our region as well as the clinical evolution of the process with the aim to compare this results with another published, specially with north European and north American studies. We followed a retrospective analysis of 184 patients diagnosed of Dupuytren Disease in our Department and an study of their clinical history looking for factors described in the medical literature in relation with the process. The results showed that 86% of patients were males with most common diagnosis in the 5th or 6th decade of the life; 64,5% were working or had had a work related with chronic hand trauma; 16% recognized familiar antecedents; 43,5% had an usual consume of alcoholic drinks; 51% smoked cigarettes; 0% suffered diabetes mellitus 1 and 28,8% diabetes mellitus 2; 1,6% epilepsy; 19% some kind of peripherical vasculopaty; 6.4% some kind of autoimmune disease; 0% degerative neurophaty; 10,3% Tunnel Carpal Syndrome; 32,1% hyperlipemia; 28,8% hyperuricemia; 3,8% liver disease; 77,7% right hand affectation, 70,1% left hand affectation and 47,3% bilateral affectation in the moment of diagnosis, most commonly affected palmar radio were 4th and 5th. Ectopic fibromatoses were an unusual found. As a conclusion, genre, age and clinical findings in our patients seem to be similar to the results presented in North American and north European series. Factors involved in the increase of oxygen free radicals like cigarettes, alcoholic drinks, diabetes melitus, hyperuricemia or peripherical vascular disease, appears in an important amount of our patients with Dupuytren Disease.