To assess the effect of changing the sodium to potassium (Na/K) ratio on blood pressure at 4 years of follow-up.The measurements were carried out under identical conditions in two study periods (2008-2010 and 2012-2014). Urinary excretion of sodium and potassium (mmol/L) over 12 nocturnal hours was used to calculate the Na/K ratio and categorized by quintile. The 24-hour sodium and potassium intake was estimated using a validated equation. The mean BP was calculated from 3 measurements after 5 minutes of rest. Of the 15,105 participants at baseline, 14,014 completed the first follow-up. Participants without validated urine collection (n=5,041), using antihypertensive medication (n=3,860) at either time points or reporting bariatric surgery during follow-up (n=45) were excluded. The differences between follow-up and baseline values were calculated for BP and the Na/K ratio. Analyses were stratified by sex and adjusted for confounding variables.Sodium intake did not change from baseline, but potassium intake increased by approximately 150mg in both sexes (P
CITATION STYLE
Pereira, T. S. S., Mill, J. G., Griep, R. H., Sichieri, R., & Molina, M. D. C. B. (2019). Effect of urinary sodium-To-potassium ratio change on blood pressure in participants of the longitudinal health of adults study-ELSA-Brasil. Medicine (United States), 98(28). https://doi.org/10.1097/MD.0000000000016278
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