Study of Various Hematological Parameters and Iron Status among Voluntary Blood Donors

Abstract

Introduction: Iron deficiency is a complication of regular blood donation. To recruit and retain regular voluntary blood donors, the iron status of the donors needs to be identified. Objective: The present study was done using a combination of hematological and iron status param- eters to detect prevalence of iron deficiency anaemia in the voluntary blood donors. Method: Complete blood count was performed on three part hematology analyzer and serum ferritin was measured by standard enzyme immunoassay technique on 393 random voluntary blood donor samples. Ferritin values below 15 µg/L were considered iron deficient, 15- 20 borderline, and above 20 normal. Results: Out of 393 donors, 111 first time and 282 repeat donors. The repeat donors were subdivided into different subgroups like as per their last donation into group I to IV, and as per their frequency of donation into group A to D. First time donors had higher mean serum ferritin levels than that in repeat donors. 28.5 % of blood donors had depleted iron stores (serum ferritin <20 μg/L) and 19.6% of donors were anemic. Serum ferritin was markedly reduced in donors > 20 time donation frequency and last donation within 3-5 months. Conclusion: There was a significant correlation between the frequency of dona- tions, last donation interval and the serum ferritin measurement so it should be included in the assessment of regular blood donors to secure adequate iron reserves in the donor population and there is a need to modify the donor acceptance criteria. Key