Mean square deviation of ICP in prognosis of severe TBI outcomes in children

Abstract

Objectives: Prognostic value of intracranial pressure (ICP) is discussed in the recent literature. The aim of our study was to find the parameter that could be representative of ICP variations and might become a good predictor of severe traumatic brain injury (TBI) outcomes in children. Materials and methods: The study included 81 patients with severe TBI (2004–2014). Inclusion criteria: GCS ≤ 8, age > 3 years old, admission time to our clinic <24 h from the time of injury. Mean daily values of ICP were used as a predictor, Glasgow outcome scale value was used as a grouping variable. Outcomes were assessed 6 months after injury. Results: Total mortality was 27%. We have entered the indicator “energy ICP” (E2), which describes the dynamics of the process and energy. E2 value in the group of survivors was <500 mmHg2; the probability of accurate forecasting was 91%. Sensitivity, 0.9; specificity; 0.94. Conclusions: The proposed method is accessible and easy to perform. This method has high specificity in the prediction of severe traumatic brain injury outcome and can be a reliable tool for ICP control.