Synthesis of 4-(Arylmethyl)proline Derivatives

Simon Loosli; Carlotta Foletti; Marcus Papmeyer; Helma Wennemers

Journal ArticleOPEN ACCESS

Synthesis of 4-(Arylmethyl)proline Derivatives

Loosli S
Foletti C
Papmeyer M
et al.

Synlett (2019) 30(4) 508-510

DOI: 10.1055/s-0037-1611672

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Abstract

A synthesis of 4 - (arylmethyl)proline by using Suzuki cross-couplings was developed. The route permits access to a variety of 4-substituted proline derivatives bearing various aryl moieties that expand the toolbox of proline analogues for studies in chemistry and biology.

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Loosli, S., Foletti, C., Papmeyer, M., & Wennemers, H. (2019). Synthesis of 4-(Arylmethyl)proline Derivatives. Synlett, 30(4), 508–510. https://doi.org/10.1055/s-0037-1611672

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Synthesis of 4-(Arylmethyl)proline Derivatives

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