The incidence and clinical significance of adenomyosis

Abstract

For more than a century the diagnosis of adenomyosis was only possible through pathological examination of hysterectomy specimens but this has changes with the introduction of transvaginal ultrasound and MRI. Despite the large number of published studies reporting on the incidence and the clinical correlates of adenomyosis, there is no agreement on the definition and cut-off between adenomyosis and normal uteri and most reports still rely on case series of women undergoing hysterectomy. This poses considerable challenge to our understanding of the disease, its impact and of the accuracy of imaging diagnosis.