Medical Therapy for Meningiomas

Abstract

If medals were given for effectiveness of treatment for progressive meningiomas from a historical perspective, medical management would collect the bronze behind radiotherapy and surgery. That placement has really not changed much today, but medical treatments do exist when surgery is not an option and patients have exhausted radiation. This chapter will highlight the historical use of hormonal/chemotherapy treatments that have most often been based on the molecular/immunologic rationale. What will be found, however, is a lack of phase III randomized trials with an abundance of small cohort and anecdotal trials that often mix benign and malignant meningiomas.