Deep learning-based hemorrhage detection for diabetic retinopathy screening

Abstract

Diabetic retinopathy is a retinal compilation that causes visual impairment. Hemorrhage is one of the pathological symptoms of diabetic retinopathy that emerges during disease development. Therefore, hemorrhage detection reveals the presence of diabetic retinopathy in the early phase. Diagnosing the disease in its initial stage is crucial to adopt proper treatment so the repercussions can be prevented. The automatic deep learning-based hemorrhage detection method is proposed that can be used as the second interpreter for ophthalmologists to reduce the time and complexity of conventional screening methods. The quality of the images was enhanced, and the prospective hemorrhage locations were estimated in the preprocessing stage. Modified gamma correction adaptively illuminates fundus images by using gradient information to address the nonuniform brightness levels of images. The algorithm estimated the locations of potential candidates by using a Gaussian match filter, entropy thresholding, and mathematical morphology. The required objects were segmented using the regional diversity at estimated locations. The novel hemorrhage network is propounded for hemorrhage classification and compared with the renowned deep models. Two datasets benchmarked the model’s performance using sensitivity, specificity, precision, and accuracy metrics. Despite being the shallowest network, the proposed network marked competitive results than LeNet-5, AlexNet, ResNet50, and VGG-16. The hemorrhage network was assessed using training time and classification accuracy through synthetic experimentation. Results showed promising accuracy in the classification stage while significantly reducing training time. The research concluded that increasing deep network layers does not guarantee good results but rather increases training time. The suitable architecture of a deep model and its appropriate parameters are critical for obtaining excellent outcomes.