Metabolomic analysis will provide the next large set of clues to further our understanding of human health and disease. A recent study has elucidated the significant differences in the metabolomes of adipocytes, serum and an adipocyte cell line after activation of two nuclear receptors, peroxisome proliferator activated receptor β/∂ (PPARβ/∂) and PPARγ. These findings hold great promise for explaining fundamental differences in the mechanisms of PPAR agonists and for identifying targets for the treatment of diabetes. © 2011 BioMed Central Ltd.
CITATION STYLE
Patterson, A. D., & Peters, J. M. (2011, August 23). PPAR action in insulin resistance unraveled by metabolomics: Potential clinical implications. Genome Medicine. https://doi.org/10.1186/gm270
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