Psychopharmacology in transplant patients

Abstract

Patients undergoing transplantation experience higher incidences of depression, anxiety, and cognitive disorders. In addition, substance use disorders might be more common and pertinent in some organ transplant candidates and recipients. Organ dysfunction, multiple comorbidities, and concurrent medications influence effects and metabolism of psychotropic medications needed to treat patients. On the other hand, psychotropic medications might cause side effects that are relevant and important to appreciate in patients with end-stage organ disease and after transplantation. Finally, medications used in transplant medicine, such as immunosuppressants, are associated with a variety of neuropsychiatric side effects. It is important for treatment providers to appreciate these important considerations, and thus this chapter covers above issues.