Azicemicins A and B, New Antimicrobial Agents Produced by Amycolatopsis: II. Structure Determination

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Abstract

A new structural class of antibiotics, azicemicins A (1) and B (2) were isolated from the culture broth of Amycolatopsis sp. MJ126-NF4. Their structures were elucidated from their physico-chemical properties, various NMR experiments and chemical transformations and were shown to be 3-(l-methyl-2-aziridinyl)-and 3-(2-aziridinyl)-3,4-dihydro-3,7,8,10,12b-pentahydroxy-9,12-dimethoxy-benz[a]anthracene-l,6(2H,5H)-dione, respectively. © 1995, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

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APA

Tsuchida, T., Sawa, R., Takahashi, Y., Iinuma, H., Sawa, T., Naganawa, H., & Takeuchi, T. (1995). Azicemicins A and B, New Antimicrobial Agents Produced by Amycolatopsis: II. Structure Determination. The Journal of Antibiotics, 48(10), 1148–1152. https://doi.org/10.7164/antibiotics.48.1148

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