Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment

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Abstract

Background: Culture-negative endocarditis due to Tropheryma whipplei is a rare disease. Mostly the diagnosis is made by histologic examination of resected heart valve tissue. Case presentation. In this case report, we described a patient with a classical Whipples disease. Transesophageal echocardiography (TEE) showed a vegetation on noncoronary cusp of the aortic valve. Whipples disease was confirmed by positive Tropheryma whipplei polymerase chain reaction (PCR) in EDTA blood and a duodenal biopsy with positive periodic acid-Schiff stain (PAS) macrophages. Conclusion: Due to timely diagnosis, our patient was treated with antibiotics without valve replacement. © 2012 Algin et al.; licensee BioMed Central Ltd.

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Algin, A., Wegdam-Blans, M., Verduin, K., Janssen, H., & Van Dantzig, J. M. (2012). Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment. BMC Research Notes, 5. https://doi.org/10.1186/1756-0500-5-600

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