Effects of bolus tube feeding on cerebral blood flow velocity in neonates

Abstract

Aim - To study continuously cerebral blood flow velocity in the middle cerebral artery before, durings and after tube feeding in neonates. Method - Cerebral blood flow velocity was measured in 14 neonates using a Doppler ultrasound device. Blood pressure, respiration, and oxygen saturation were monitored. Results - Mean blood flow velocity decreased from 37 cm/s before feeding to 33 cm/s (P<0.001) 5 to 11 minutes after feeding. Prefeeding values were reached after 17 minutes. Arterial blood pressure, respiration patterns, and oxygen saturation did not change significantly during the study period. Conclusion - Tube feeding in preterm infants may decrease cerebral perfusion, despite unchanged blood pressure and unchanged oxygen saturation.