Abstract
Phosphoinositides (PIs), a family of phosphorylated derivatives of the membrane lipid phosphatidylinositol, are established regulators of multiple cellular functions. An increasing amount of evidence has highlighted potential links between PI-mediated signaling pathways and the etiology of many human diseases, including cardiovascular pathologies. This chapter will provide a detailed overview of the peculiar functions of the major cardiovascular PIs in the pathogenesis of atherosclerosis, heart failure, and arrhythmias. © 2012 Springer Science+Business Media Dordrecht.
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CITATION STYLE
Ghigo, A., Perino, A., & Hirsch, E. (2012). Phosphoinositides and cardiovascular diseases. Current Topics in Microbiology and Immunology, 362, 43–60. https://doi.org/10.1007/978-94-007-5025-8_2
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