Primary central nervous system post-transplant lymphoproliferative disorder diagnosed by peripheral facial nerve palsy

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Abstract

Although primary central nervous system post-transplant lymphoproliferative disorder (PCNS-PTLD) causes various symptoms depending on the tumor region, there has been no previous report of PCNS-PTLD in the cerebellopontine angle that was diagnosed due to peripheral facial nerve palsy. We herein report a case involving a 62-year-old man with PCNS-PTLD in the cerebellopontine angle who was diagnosed due to peripheral facial nerve palsy. The reduction of immunosuppressive therapy, whole-brain radiotherapy, intrathecal chemotherapy, and rituximab were effective in treating this patient. Physicians should therefore be mindful that PCNS-PTLD can cause peripheral facial nerve palsy in renal transplant recipients.

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Imafuku, A., Tanaka, K., Marui, Y., Ubara, Y., Takaichi, K., Tomikawa, S., … Ishii, Y. (2018). Primary central nervous system post-transplant lymphoproliferative disorder diagnosed by peripheral facial nerve palsy. Internal Medicine, 57(13), 1899–1903. https://doi.org/10.2169/internalmedicine.9613-17

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