Obesity is an independent risk factor for chronic diseases such as diabetes, cardiovascular diseas-es and certain cancers. Early detection of abdominal obesity followed by appropriate interven-tions will prevent associated diseases. The objective was to determine optimal waist circumfe-rence (WC) cut-off points predictive of at least one other component of metabolic syndrome in Be-nin adults. This longitudinal and observational study included at the baseline 541 apparently healthy subjects aged 25 -60 years randomly selected in the largest city of Cotonou (n = 200), the smaller-size city of Ouidah (n = 171) and rural surroundings of Ouidah (n = 170) in Benin. Com-ponents of the metabolic syndrome considered along with abdominal obesity were high blood pressure, high fasting glycaemia, low HDL-cholesterol and high triglycerides as defined by the Joint Interim Statement. After the baseline survey, the subjects were followed-up for four years. Complete data at baseline and four years later were available in 416 subjects. The receiver oper-ating characteristic (ROC) curve for waist circumference to predict at least one other component of the metabolic syndrome was plotted and the Youden index was used to define the optimal cut-offs of WC. At the baseline of the study, the optimal WC cut-off point to predict the presence of at least one other component of the metabolic syndrome was 80 cm for men (sensitivity = 0.62, specificity = 0.65); the area under the ROC curve was 0.67 (IC 95%: 0.61 -0.74). In women, the op-timal WC cut-off point was 90 cm (sensitivity = 0.54, specificity = 0.80), and the area under the ROC curve was 0.68 (IC 95%: 0.62 -0.75). These optimal cut-offs were similar four years later. Opti-mum WC cut-off points for both men and women in Benin differ from those currently recom-mended for sub-Saharan Africans. Therefore, waist circumference cut-off points for abdominal obesity need to be reconsidered for these populations.
Agueh, V. D., Sossa, C., Ouendo, D. M.-E., Paraizo, N. M., Azandjemè, C., Kpozehouen, A., … Delisle, H. (2015). Determination of the Optimal Waist Circumference Cut-Off Points in Benin Adults. Open Journal of Epidemiology, 05(04), 217–228. https://doi.org/10.4236/ojepi.2015.54026