Ocular Blood Flow Autoregulation Mechanisms and Methods

100Citations
Citations of this article
131Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

The main function of ocular blood flow is to supply sufficient oxygen and nutrients to the eye. Local blood vessels resistance regulates overall blood distribution to the eye and can vary rapidly over time depending on ocular need. Under normal conditions, the relation between blood flow and perfusion pressure in the eye is autoregulated. Basically, autoregulation is a capacity to maintain a relatively constant level of blood flow in the presence of changes in ocular perfusion pressure and varied metabolic demand. In addition, ocular blood flow dysregulation has been demonstrated as an independent risk factor to many ocular diseases. For instance, ocular perfusion pressure plays key role in the progression of retinopathy such as glaucoma and diabetic retinopathy. In this review, different direct and indirect techniques to measure ocular blood flow and the effect of myogenic and neurogenic mechanisms on ocular blood flow are discussed. Moreover, ocular blood flow regulation in ocular disease will be described.

Cite

CITATION STYLE

APA

Luo, X., Shen, Y. M., Jiang, M. N., Lou, X. F., & Shen, Y. (2015). Ocular Blood Flow Autoregulation Mechanisms and Methods. Journal of Ophthalmology. Hindawi Publishing Corporation. https://doi.org/10.1155/2015/864871

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free