Central serous chorioretinopathy

Abstract

Central serous chorioretinopathy (CSC) was originally described by Albrecht von Graefe in 1866 as “central recurrent retinitis” (Von Graefe 1866). Since then our understanding of CSC has progressed considerably. Gass in 1967 named the disease as central serous chorioretinopathy and proposed choriocapillaris hyperpermeability as the cause of CSC (Gass 1967). This hypothesis was later supported by studies using indocyanine green angiography (ICGA) which showed multifocal areas of choroidal vascular hyperpermeability in eyes with CSC.