TRYPSIN, RUTOSIDE AND BROMELAIN ALONE AND FIXED DOSE COMBINATION: A NATURAL, SAFER AND EFFECTIVE ANTI-INFLAMMATORY AGENT

Abstract

Millions of patients worldwide with chronic musculoskeletal symptoms are on long term therapy with non-steroidal anti- inflammatory drugs (NSAIDs). But the unfortunate fact is that these drugs have common and potentially severe adverse effects, including renal impairment, gastrointestinal complications and cardiotoxicity. The cardiotoxic effect produced by these drugs is particularly worrying because many patients have both cardiovascular disease and musculoskeletal disease. Clinicians and medical researchers worldwide are in general agreement that pharmacologic pain treatment for musculoskeletal conditions is unsatisfactory and the irrationale use of NSAIDs in such conditions is adding the agony of the patients. Thus new drugs are needed to replace NSAIDs to treat musculoskeletal diseases. Newer natural and safer alternatives identified in recent past are Bromelain, Trypsin and Rutoside. Their combination to treat inflammatory diseases is a coming out with promising results