Renal scarring in spinal cord injury: A progressive process?

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Abstract

Study design: A retrospective analysis. Objectives: To examine the natural history of renal scarring in the spinal cord injured population. Setting: United Kingdom. Methods: All spinal cord injured patients with renal scars at our establishment were considered eligible. A total of 27 patients with renal scars were identified. No patient had renal scarring at presentation on radiological imaging. All patients had annual renal imaging with a mean follow up period of 19.1 years. The presence of new scars was considered as evidence of progression. Results: In all, 59% of kidneys developed renal scars with a mean time interval between spinal injury and renal scar development of 13 years. Of these kidneys with scars, only 15.6% demonstrated progression of the scarring process. There were no deaths due to renal causes. Conclusion: The aetiology of renal scarring is multifactorial. The findings of this study suggest that renal scarring in the spinal cord injured population is predominantly a nonprogressive process once a scar has developed. This is in concordance with the belief that renal scarring in the paediatric population with vesicoureteric reflux is also a stable, nonprogressive process. © 2006 International Spinal Cord Society All rights reserved.

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APA

Edhem, I., & Harrison, S. C. W. (2006). Renal scarring in spinal cord injury: A progressive process? Spinal Cord, 44(3), 170–173. https://doi.org/10.1038/sj.sc.3101831

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