Abstract
The cerebrospinal fluid (CSF) perfuses the brain and spinal cord. CSF contains proteins and peptides important for brain physiology and potentially also relevant for brain pathology. Hence, CSF is the perfect source to search for new biomarkers to improve diagnosis of neurological diseases as well as to monitor the performance of disease-modifying drugs. This chapter presents methods for SELDI-TOF profiling of CSF as well as useful advice regarding pre-analytical factors to be considered. © 2012 Springer Science+Business Media, LLC.
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Simonsen, A. H. (2012). Protein profiling of cerebrospinal fluid. Methods in Molecular Biology, 818, 109–117. https://doi.org/10.1007/978-1-61779-418-6_8
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