Paper for microfluidics: Selection criteria

Abstract

Microfluidics is promising for point of detection in healthcare applications involving silicon-based MEMS technology in combination of materials like PDMS and glasses involving complex fabrication processes. High cost and sensitivity is a major concern for the next stage development of microfluidic devices. Paper based microfluidics is being pursued to overcome fabrication complexities and making point of care detection cost effective and for one-time usage to avoiding disease infection. The use of cellulose paper on biomedical applications is a strong interest towards low cost fabrication. Microfluidics Paper based Analytical Devices (μ-PAD) are being developed for healthcare sector with global applicability. Understanding of paper structures and their physical, chemical properties play crucial role in designing micro patterns for microfluidics applications. In this paper, we have presented the selection criteria of paper as a substrate material for microfluidic applications based on their theoretical and experimental study.