Using metallic impregnation, Camillo Golgi (1898) discovered in the cytoplasm of nerve ganglion cells a new cell organelle that formed an extensive perinuclear network: the appareil reticulaire interne. With the empirical and non-specific methods used for its demonstration, the Golgi apparatus was not easily detected in living cells (reviews in Beams and Kessell (1968), Whaleyand Dauwalder(1979), Farquharand Palade (1981) Mollenhauer and Morre (1991), Berger (1997)). It was the merit of Dalton and Felix (1954) to demonstrate with the electron microscope that the Golgi apparatus was not an artefact. It appeared instead as a system of stacks of closely apposed lamellae or saccules usually encountered in the juxtanuclear area of mammalian cells. With the improvement of the fixation and staining techniques, it became clear that an organelle made up of stacked flattened saccules (cisternae) and vesicles could be seen in most cells.
CITATION STYLE
Rambourg, A., Daraspe, J., Képès, F., & Verbavatz, J. M. (2008). Morphodynamics of the yeast Golgi apparatus. In The Golgi Apparatus: State of the Art 110 Years after Camillo Golgi’s Discovery (pp. 630–646). Springer-Verlag Wien. https://doi.org/10.1007/978-3-211-76310-0_37
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