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Targeted stem cell based RANTES/TK suicide gene-therapy in a murine pancreatic cancer tumour model

  • Zischek C
  • Niess H
  • Ischenko I
  • et al.
DOI: 10.1007/978-3-642-00625-8_2
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Abstract

… TK leads to phosphorylation and therefore activation of intra- peritoneally administered ganciciclovir (GCV) which then leads to cell death of the integrated stem cells, as well as to cell death of tumour cells by the so called bystander effect [5]. Material and Methods: MSCs were …

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Zischek, C., Niess, H., Ischenko, I., Eichhorn, M., Jauch, K. W., Nelson, P., & Bruns, C. J. (2009). Targeted stem cell based RANTES/TK suicide gene-therapy in a murine pancreatic cancer tumour model (pp. 3–5). https://doi.org/10.1007/978-3-642-00625-8_2

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